Artificial Intelligence (AI) is transforming the lives of differently abled individuals by enhancing accessibility, independence, and inclusion. AI has proven role in assistive technologies like advanced prosthetics, communication devices, and smart home devices, which help overcome physical and communication barriers. This article highlights AI's impact on digital accessibility, healthcare, and employment opportunities. Despite these advancements, challenges such as the percolation of social biases in the algorithms through the data the models are trained with, data privacy concerns, and unequal access must be addressed. AI can continue to improve the quality of life for people with disabilities by prioritizing ethical development and thus can foster greater social equity.