Vitiligo in childhood carries emotional, social, and psychological implications not only for the child but also for parents, who often experience anxiety, guilt, fear, and socioeconomic stress. These parental emotional states significantly influence the child’s coping ability, health-seeking behaviour, adherence to treatment, and overall disease trajectory. Homoeopathic philosophy, particularly Hahnemann’s understanding of susceptibility, miasmatic influences, and psychosomatic integration, offers an interpretive framework for understanding how parental mental states interplay with the child’s constitutional disposition. This literature review synthesises global psychosocial research and classical Homoeopathic thought to present a comprehensive, multidisciplinary understanding of parental emotional burden in childhood vitiligo. The review highlights sociocultural stigma, parental distress patterns, psychodermatological insights, and Homoeopathic interpretations, emphasising the familial mental milieu. The objective is to enhance clinician awareness and promote holistic assessment models that are applicable in both clinical and community practice.