Alzheimer’s disease (AD) is a neurodegenerative disorder in humans, which is the world’s most prevalent form of dementia, that leads to loss of memory and cognition, death of neurons, loss of synapses and damage to the brain, which culminates in death.  As the world grapples with the rising incidence and a general concern for cognitive decline, while conventional medicine focuses on symptomatic management, siddha medicine emphasizes proactive measures to maintain the health of nervous system (Naadi mandalam) and prevent onset of debilitating conditions. In a world where Alzheimer’s presents a growing challenge, the wisdom of Siddha strategies such as 1) Nithya and Kaala ozhukam (Daily & Seasonal regimens), the core idea of modifications in life style in corelation with the natural rhythms of the seasons contributes proper balance of doshas, eliminates toxins, strengthens neural connection and supports overall vitality by addressing the root causes of imbalances and contributing to preserve neuronal integrity and enhances cognitive reserve preventing AD.