Based on various sources, deserts contributed 13 to 33% part of the global terrestrial surface. The desert area is larger than the area of all wetlands and tropical forests combined. The Indian desert, or Thar desert harbor numerous plants, many occurring in wild conditions. The Malpura block covers a large area and contains a diversity of desert plants and animals. Vegetation of Malpura block is diverse in various places, and Sand, hills and water bodies contain biodiversity. In the study area, semi-arid conditions occur in Malpura, and the result is that many desert plants grow in this area. Many desert plants are used as medicines, fuel, food, fodder, making items, etc. The present study and research are to investigate the ecological and ethnobotanical values of many desert plants that belong to different families throughout the year. The major desert plant families were Fabaceae, Asclepiadaceae, Cucurbitaceae, Rhamnaceae, Cactaceae, Arecaceae, Liliaceae, Asparagaceae, Amaranthaceae, etc. The most abundant desert plants were Acacia spp. Prosopis cineraria, P. julifora, Crotalaria burhia, Calotropis procera, Leptadenia pyrotechnica, Momordica dioica, Corollocarpus epigaeus, Cucumis melo var., Euphorbia caducifolia, Opuntia dillenii, Ziziphus nummularia, Capparis decidua, Aerva persica, Phoenix dactylifera, Aloe vera etc.